Hot answers tagged differential-analysis
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There are 256! possible 8x8 S-boxes (i.e., bijective functions from $\{0,1\}^8$ to $\{0,1\}^8$. This is an absolutely enormous number. You couldn't possibly enumerate all of them within the lifetime of the universe. So, yes, this is one reason why it is not straightforward to determine whether there exists such a S-box with differential uniformity 2.
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