Suppose $p_0$ and $q_0$ are known prime numbers and define $p_i$ and $q_i$ as follows:
$$p_{i+1} = next\_prime(p_i^2 + q_i^2), \qquad i \ge 0$$ and
$$q_{i+1} = next\_prime(2p_iq_i), \qquad i \ge 0$$ and $$N_{i+1} = p_{i+1}q_{i+1}, \qquad i \ge 0$$
I want to know is there efficient algorithm to factor $N_{i}$? What happen when the $p_0$ and $q_0$ be unknown? So can we factor an integer $N_1$ for example for unknown $p_0$ and $q_0$?