The question asks if $\operatorname{SHA-1}(M)\bmod n$ is random, giving the example of $n=2^{80}$.
I'll consider arbitrary $M$ (that is, determined without knowledge of SHA-1, or just of SHA-1's 160-bit initialization constant), and that it makes $\operatorname{SHA-1}(M)$ indistinguishable from $160$ random bits (which is true from a computational perspective, baring any huge theoretical progress).
When $n=2^k$ for $0\le k\le160$ (including $n=2^{80}$ in the question), $\operatorname{SHA-1}(M)\bmod n$ is simply the integer with binary representation the $k$ low-order bits of $\operatorname{SHA-1}(M)$, thus is indistinguishable from $k$ random bits (proof sketch: an hypothetical efficient distinguisher for $\operatorname{SHA-1}(M)\bmod n$ can be turned into an efficient distinguisher for $\operatorname{SHA-1}(M)$).
For other $n$ of interest, that is $n=s\cdot2^k$ with odd $s>1$ and $\log_2(s)+k<160$, the low-order $k$ bits of $\operatorname{SHA-1}(M)\bmod n$ are the low-order $k$ bits of $\operatorname{SHA-1}(M)$, and similarly indistinguishable from $k$ random bits. However $\operatorname{SHA-1}(M)\bmod n$ is not uniformly random over the set $\{0\dots(n-1)\}$: low values are more likely than high values. When $n=3\cdot2^{158}$, odds that $\big(\operatorname{SHA-1}(M)\bmod n\big)<{n\over3}$ are $1\over2$, rather than $1\over3$ for a uniform distribution. For example, the generator specified by FIPS 186-1 Appendix 3.1 has such bias (but it does not matter much in the application).
Update: a comment asks a simple algorithm based on SHA-1 that, given an arbitrary input $M$, outputs an integer uniformly random on the set $\{0\dots(n-1)\}$ for some parameter $n$ with $0<n\le2^{160}$.
As previously stated, when $n$ is a power of two, we can use $\operatorname{SHA-1}(M)\bmod n$. This is also the case when $n<2^{90}$ or so, because the adversary gets a negligible advantage for computationally reasonable effort.
Whatever $n$, we can use the following:
- $r\gets 0$ ($r$ is expressed as a 16-byte string)
- repeat $h\gets\operatorname{SHA-1}(r\|M)$ and $r\gets r+1$ until $h\ge(2^{160}\bmod n)$
- output $h\bmod n$.
The output is uniformly random based on the fact that in the final step, $h$ is uniformly random on the set $\{(2^{160}\bmod n)\dots(2^{160}-1)\}$, which contains a number of elements multiple of $n$.