Well, consider if Bob is communicating with Alice; Bob sends Alice a random $r^e$, Alice recovers $r$ and sends it back. Then, they proceed to use the same RSA modulus to negotiate a secret key; for example, Bob picks a secret value $m$, computes $m^e$, sends that to Alice, who recovers $m$, and then they both use $m$ to generate secret keys, and use those keys to exchange messages that they want to keep secret.
Here's what can happen; the NSA can then start communicating with Alice; they can send Alice the value $m^e$, Alice (thinking that this is someone else she is supposed to be talking to) recovers $m$, and sends it back. The NSA now has enough information to recover the secret keys that Alice and Bob used to communicate.
And, if you're thinking "well, can't Alice remember the values that she used to communicate with Bob, and refuse to decrypt that", it turns out that's not sufficient. What the NSA can do is pick a random value $k$, compute $k^e$, and send the value $k^e \cdot m^e = (km)^e$. Alice will recover the value $km$, which will look like a random selection, and send that back; the NSA can then compute $km \cdot k^{-1} = m$, and is then able to decrypt the secret traffic.