I want a deterministic PRNG for simulation purposes, and I don't want to have to worry about spurious correlations like those the DMCT is designed to protect the Mersenne Twister against. So even though I don't care about cryptographically secure random numbers, a cryptographically secure Deterministic Random Bit Generator seems like the way to go.
For this purpose, I am thinking of using pycrypto's Crypto.Random.Fortuna.FortunaGenerator. It only allows $2^{16}$ blocks of pseudorandom data before reseeding because it uses an AES stream in counter mode. Since I care only about its resemblance to uniform independent draws and not about the entropy which would secure it from cryptographic attack, is there any harm in seeding the generator from its own output?