The sender encrypts the data with a symmetric key. After that, he encrypts (using RSA algorithm) this symmetric key with the public asymmetric key of the receiver.
That's one possible implementation of a hybrid cryptosystem for encryption/decryption. It is also quite common to derive the symmetric key using the asymmetric key pair. This is performed for instance by IES for Diffie-Hellman based cryptography but also by RSA-KEM.
How does the sender know the public asymmetric key of the receiver?
- Diffie Hellman.
No, Diffie-Hellman is used to derive symmetric keys. It cannot be used to distribute public keys.
How does the sender know the public asymmetric key of the receiver?
- Digital certificate PKI, by querying a CA.
An implementation of a PKI could certainly work.
But PKI doesn't necessarily mean that there are CA's (e.g. see how PGP operates).
And if they do exist - for instance in PKI-X used in e.g. browsers - then they generally are only needed to sign certificate requests and verify that certificates are not revoked. During operation the CA certificates can simply be send using a certificate chain. Quering a CA is not required at the time of verification.