It looks like you're asking the following:
Consider the following families of distributions over functions from $\{0,1\}^{n} \to \{0,1\}^{n}$:
$\{X_n\}, \text{ where } X_n \text{ is the uniform distribution over the set of functions } f : \{0,1\}^{n} \to \{0,1\}^{n} \text{ such that } f(0^{n}) = 0^{n} $
$\{Y_n\}, \text{ where } X_n \text{ is the uniform distribution over the set of functions } f : \{0,1\}^{n} \to \{0,1\}^{n} \text{ such that } f(0^{n}) \neq 0^{n} $
Are these families of distributions computationally indistinguishable?
I claim they are computationally distinguishable, assuming that each function can be evaluated on input $0^{n}$ efficiently. Consider the following distinguisher, which on input $f$ computes $f(0^{n})$ and outputs $X$ if $f(0^{n}) = 0^{n}$ and $Y$ otherwise. By the definition of $\{X_n\}$, if $f$ is drawn from this family, this distinguisher will output $X$. By the definition of $\{Y_n\}$, if $f$ is drawn from this family, this distinguisher will output $Y$.